Nijmegen periodic fever research group

Hyper-IgD and periodic fever syndrome (HIDS)

Third International Workshop

Twenty years HIDS

This meeting was also held on the occasion of the Ph.D. defense ceremony of Anna Simon, on her thesis entitled “Hereditary Autoinflammatory Syndromes, with an emphasis on Hyper-IgD and periodic fever syndrome”. Participants were invited to attend this ceremony in the afternoon.

 

PROGRAM

 

10.30 Registration; coffee/tea

11.00 Opening of the symposium
Jos W.M. van der Meer, Nijmegen, the Netherlands

 

Morning program

Chairman: Jos W.M. van der Meer, Nijmegen, the Netherlands

 

11.10 Clinical diagnosis and differential diagnosis of HIDS
Joost Frenkel, Utrecht, the Netherlands

11.35 Pathogenesis of hereditary autoinflammatory syndromes
Daniel Kastner, Bethesda, MD, USA

12.10 Apoptosis in HIDS
Evelien J. Bodar, Nijmegen, the Netherlands

 

12.35 Lunch

 

Afternoon program

Chairman: Richard J. Powell, Nottingham, UK

 

13.20 Regulation of isoprenoid metabolism
Hans Waterham, Amsterdam, the Netherlands

13.45 Treatment strategies in HIDS and other hereditary autoinflammatory syndromes
Joost P.H. Drenth, Nijmegen, the Netherlands

14.20 Amyloidosis in HIDS
Jeroen C.H. van der Hilst, Nijmegen, the Netherlands

 

14.50 Tea or coffee

 

15.30 PhD ceremony Anna Simon
Thesis “Hereditary Autoinflammatory Syndromes”

16.45h Reception

In 2004, it was exactly twenty years after the first description of HIDS by Jos W.M. van der Meer and his colleagues in The Lancet, and five years since the publications on the discovery of the gene defect involved, mevalonate kinase, in Nature Genetics. We marked this occasion with an up-to-date symposium on HIDS.

Research in HIDS has increased rapidly in recent years, mirroring that of periodic fever syndromes in general, and this has had a direct impact on clinical care of patients with this syndrome. These new developments, ranging from bench to bedside, were highlighted at the meeting. The program was of interest to clinicians caring for HIDS patients as well as scientists with an interest in hereditary autoinflammatory syndromes, the isoprenoid metabolism or inflammation in general.

Nijmegen, 4 November 2004